Regenerative Medicine


Scientists and doctors have made tremendous advances to make tissue regeneration a reality in treating many diseases. Through regenerative medicine, a person can take advantage of their body’s ability to heal itself by using the healthy adult stem cells that can be found throughout the body.

Laboratory and clinical research has shown that it is possible to use adult stem cells to restore lost, damaged or ageing cells and effectively regenerate tissue in the body. Regenerative therapies are showing promise in the treatment of orthopedic pain.

Adult stem cells were discovered over 40 years ago when researchers found that cells derived from bone marrow had the ability to form various tissues. Adult stem cells are early stage cells and under the right conditions, are capable of developing into other types of cells with the potential to regenerate damaged tissue.

Adult stem cells are being used to treat many types of chronic pain and degeneration. Currently doctors are treating shoulder, knee, hip, and spine degeneration, in addition to soft tissue (muscle, tendon, ligament) and other bone related injuries.

What is regenerative medicine?

When injured or invaded by disease, our bodies have an immediate response to heal and fight, so what if it was possible to accelerate the power of the body to heal itself and improve the process in a clinically relevant way? Regenerative medicine in Coral Springs tries to find such solutions.

Regenerative medicine aims to restore the structure and function of damaged tissues and organs. It is also working to create remedies for organs that have become permanently damaged. The goal of this medicine is to find a way to cure previously untreatable injuries and diseases.

Scientific research is working to make regenerative medicine treatments available for clinical use. Treatments include both in vivo and in vitro procedures; in vivo procedures include studies and trials performed inside the living body in order to stimulate previously damaged organs to heal themselves, while in vito treatments are applied to the body through implantation of a solution developed inside a laboratory.

What are regenerative medicine treatments?

Regenerative medicine in practice takes three interrelated approaches:

  • Rejuvenation

    • Rejuvenation means boosting the body’s natural ability to heal itself. Unlike your skin, which heals within a few days after a cut, other organs don’t repair themselves as fast and may need supportive treatments–regenerative medicine provides such solutions.
  • Replacement

    • Replacement involves using healthy cells, tissues, or organs from a living or deceased donor to replace damaged ones. Organ transplants, such as heart and liver transplants, are good examples.
  • Regeneration

    • Regeneration involves delivering specific types of cells or cell products to diseased tissues or organs, where they will ultimately restore tissue and organ function. This can be done through cell-based therapy or by using cell products, such as growth factors. Bone marrow transplants are an example.

The role of stem cells in regenerative medicine

Stem cells are cells that have the ability to develop (through a process called differentiation) into many different types of cells, such as skin cells, brain cells, lung cells and so on. Stem cells are a key component of regenerative medicine in Coral Springs, as they open the door to new clinical applications.

Regenerative medicine teams are studying a variety of stem cells, including adult and embryonic stem cells. Embryonic stem cells exist only at the earliest stages of development, while various other types of tissue-specific (or adult) stem cells appear during fetal development and remain in our bodies throughout life.

Many of the regenerative therapies under development in Coral Springs begin with an individual patient’s own cells. For example, a patient’s own skin cells may be collected, reprogrammed in a laboratory to give them certain characteristics, and delivered back to the patient to treat his or her disease.

Frequently Asked Questions 

In adults, stem cells are present within variety of tissues and organs, the most common sources being bone marrow and fat (or adipose) tissue.

One of the richest sources of adult stem cells is bone marrow, and the hip (pelvis) is one of the best and most convenient locations for obtaining bone marrow. In the harvesting procedure, the doctor typically removes (or aspirates) from the pelvis. A rained nurse or technician then uses specifically designed equipment to concentrate the adult stem cells in the bone marrow and provides the cells back to the physician for implantation at the site of injury.

No, since they are cells collected from your own tissue, there is little threat of rejection.


There are many potential applications where stem cell treatments can be very effective. The following are the most common:


While adult stem cells have been used for decades to treat a variety of diseases, their application in the treatment of pain is relatively new. Because of this, insurance companies do not currently cover the therapy.

The cost of a stem cell treatment varies based on the procedure performed. Our office staff can assist you with payment options and any other questions you may have.

Meet Dr. Pohlman 

Dr. Dane C. Pohlman is board-certified in Physical Medicine and Rehabilitation. He completed an ACGME accredited pain fellowship at Montefiore Hospital/Albert Einstein in New York City. He completed his residency in Physical Medicine and Rehabilitation at MedStar Georgetown University Hospital in Washington, D.C. Dr. Pohlman’s professional interests include a comprehensive and physiatric approach to pain management. He accomplishes this using a variety of interventional techniques to treat the spine, peripheral joint disease, and chronic pain, with the goal of restoring and maximizing both function and quality of life to his patients.

A letter from Dr. Pohlman

Dear Patient,
As your healthcare provider, it is my medical obligation to provide you with all the current treatment options available. Over the past decade, the medical field has benefited from stem cell research. These scientific findings have given way to the new, exciting field of
Regenerative Medicine. This field focuses on the use of adult stem cells to aid in the repair of damaged tissue, such as bone, tendons and ligaments.

I believe the use of your own (autologous) adult stem cells is a safe and effective treatment option. Adult stem cells offer not only an effective treatment for damaged
tissue, but also can be used to prevent further tissue degeneration.

This brochure includes valuable information about adult stem cells and their awesome potential. Please review it and come to me with any questions that you may have.

Dane Pohlman, DO[/column]

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